Bluestone Trials

Oral Cancer Biomarker Study

Do you have oral pre-cancer or cancer?
Status: Currently recruiting subjects.

Seeking volunteers to take part in a study exploring the causes of oral cancer and oral cancer pain

Oral cancer presents a significant health problem.  The 5-year survival rate for oral squamous cell carcinoma is 40% and is among the worst of all sites in the body. This survival rate has not improved over the past 40 years.  Early detection and treatment profoundly impact survival; however there are currently no genetic markers available to identify pre-cancer and cancer.

The purpose of this study is to find what leads to cancer pain by examining the proteins in blood, saliva, urine, fluid, and tissue produced by oral cancer.  This may help doctors to provide very specific therapy for oral cancer and pain. This study will compare the bio-fluids and tissues in oral cancer and oral pre-cancer patients, and healthy volunteers.

Study Details:

You may be eligible to participate in this study if you have been recently diagnosed with a suspicious lesion in your mouth, are at least 18 years of age, not pregnant or lactating, and have never previously been treated for head or neck cancer with chemotherapy and/or radiation.

For patients diagnosed with oral cancer who are scheduled for surgery, this study consists of 3 visits over a period of 3 months.

For patients diagnosed with oral pre-cancer and are scheduled for tissue biopsy, this study consists of 2 visits over a period of 2 months.

This study is also recruiting healthy volunteers who are scheduled for teeth extraction or corrective jaw surgery at the NYU College of Dentistry. For this group of participants, this study consists of 1 visit, which will take place at the same time as your scheduled visit to the dental clinic. 


Interested in participating?

If you, a family member, or someone you know is interested in this study, please contact our clinical research coordinator at the Bluestone Center at 212-998-9310. Or, fill out our contact form. We will get back to you as soon as possible. Confidentiality will be maintained for all applicants and participants.