Bluestone Trials

Sjogren's Syndrome Study

Do you have Sjogren’s Syndrome?
Status: Completed.

If you are at least 18 years of age and interested in gaining more knowledge of Sjogren’s Syndrome (an autoimmune disease), you may be eligible to participate in this study.


Study Details:


Interested participants should be diagnosed with Sjogren’s Syndrome prior to participation in this study.


This study consists of one visit for approximately one to two hours at our study site, where the eligible participant will be asked to provide a sample of saliva as well as, answer medical history questions. Eligible participants will be compensated for time and travel expenses, if they qualify for the study.


Sjogren’s Syndrome is an autoimmune disease in which the body's immune system mistakenly attacks its own moisture producing glands (such as the salivary glands). The hallmark symptoms are dry eyes and dry mouth. Sjogren’s may also cause disorders of other organs, affecting the kidneys, GI tract, blood vessels, lung, liver, pancreas, and the central nervous system. Many patients experience debilitating fatigue and joint pain. Symptoms can plateau, worsen, or go into remission. While some people experience mild symptoms, others suffer debilitating symptoms that greatly impair their quality of life.Sjogren’s is one of the most prevalent autoimmune disorders, striking as many as 4,000,000 Americans. Nine out of ten patients are women. The average age of onset is late 40’s although Sjogren’s occurs in all age groups in both women and men.

Study Background:

About 50% of the time, Sjogren’s Syndrome occurs alone, and 50% of the time, it occurs in the presence of another connective tissue disease. Common diagnoses that co-exist with Sjogren’s Syndrome are Rheumatoid Arthritis, and Systemic Lupus, among others. All instances of Sjogren’s Syndrome are systemic, affecting the entire body.