Bluestone Trials

Dry Mouth Study

Do you suffer from dry mouth and would like to test new products that might help increase the amount of saliva that you have in your mouth?
Status: Completed.

We are conducting a clinical trial to test a new treatment for the relief of dry mouth symptoms. The purpose of this study is to test how well an over the counter adhesive disc placed inside your mouth works to help relieve dry mouth symptoms and freshen breath.

Study Details:  

If you are experiencing dry mouth symptoms and are at least 18 years of age, you may be eligible to participate in this research study at no cost to you. This study consists of 6 visits at our study site over 5 weeks. Qualifying participants can be compensated for time and travel expenses.

Study Background:

When we don't produce enough saliva, our mouth gets dry and very uncomfortable. Dry mouth may be associated with severe decreases in quality of life including difficulty in chewing, swallowing, wearing dentures, taste and speech. Dry mouth might also increase the risks of developing dental caries (tooth decay) and oral fungal infections (candidiasis). The major causes of dry mouth are medications (prescription and non-prescription), including drugs used to treat depression, anxiety, pain, allergies and colds (antihistamines and decongestants), obesity, acne, epilepsy, hypertension (diuretics), diarrhea, nausea, psychotic disorders, urinary incontinence and asthma.

Dry mouth can also be a side effect of systemic diseases, including Sjogren's syndrome, HIV/AIDS, Alzheimer's disease, diabetes, anemia, cystic fibrosis, rheumatoid arthritis; or a side effect of certain medical treatments that can damage the glands that produce saliva, for example radiation for head and neck cancer and chemotherapy treatments.