Bluestone Trials

Nighttime Heartburn Study

Is nighttime heartburn keeping you awake?
Status: Completed.

If you are at least 18 years of age and experienced nighttime heartburn at least two days and nights per week over the past month, you may qualify to participate in a research study at the NYU Bluestone Center for Clinical Research aimed at helping individuals who suffer with nighttime heartburn.

Study Details: 

This study consists of five visits to our study site, over a six-week period. If eligible, participants can be compensated for time and travel expenses.


A telephone survey conducted on 1000 heartburn sufferers on behalf of the American Gastroenterological Association demonstrated that 78% of heartburn sufferers had nighttime heartburn and that nighttime heartburn is associated with a diminished quality of life.


Heartburn occurs in many patients when acidic stomach contents move into the esophagus from the stomach causing a burning sensation in the chest or throat. The risk factors for heartburn symptoms include obesity, spicy foods, stress, alcohol, overeating, pregnancy and family history.


Doctors at the NYU Bluestone Center for Clinical Research are evaluating an investigational medication for the treatment of frequent heartburn as part of a medical research study. Qualified participants will receive a study-related medical evaluation and the investigational medication at no cost.