Bluestone Trials

HIV Research Study

Seeking HIV-positive and HIV-negative participants
Status: Completed.

PLEASE NOTE: We can no longer accept new participants for this study. 

The purpose of this study is to examine HIV's effect on the digestive tract and the mouth. This study will examine the changes that occur in the mouth which are related to the treatment of HIV disease. 

In order to examine these changes we need participants who are HIV-positive.  We also need participants who are HIV-negative so that we can compare findings with HIV-positive participants before they begin treatment with anti-HIV drugs.

Participants are being asked to volunteer in this study either because they have been diagnosed with HIV infection and are about to start receiving antiretroviral treatment, or they have been tested for HIV infection and are HIV-negative.

An optional gastrointestinal sub-study is included in the project. The purpose of this sub-study is to determine whether HIV-positive subjects have increased amounts of inflammation throughout their stomach and intestines compared to healthy HIV-negative subjects.

Study Details:

This study will have 2 groups: HIV-positive participants and HIV-negative participants.  We are looking for HIV-positive participants who are ready to start or restart medication.  HIV-positive participants will have 9-10 visits between 30 minutes to 2 hours per visit within a 2 year period.  HIV-negative participants that have tested negative will have 3 visits between 30 minutes to 2 hours per visit within a 6 month period. Each visit may involve a collection of saliva, blood, and/or tissue plaque.

Free dental exam and compensation will be provided for eligible participants.

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